The University of Chicago Header Logo

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following properties of Mcnerney, Megan
PropertyValue
keywords Myeloid Leukemia
One or more keywords matched the following items that are connected to Mcnerney, Megan
Item TypeName
Concept Base Sequence
Concept DNA Mutational Analysis
Concept Genes, MHC Class I
Concept Nucleic Acid Conformation
Concept Major Histocompatibility Complex
Concept Genes, ras
Concept Transcription, Genetic
Concept Leukemia, Myeloid
Concept Genes, Tumor Suppressor
Concept Leukemia, Myeloid, Acute
Concept Consensus Sequence
Concept Evolution, Molecular
Concept Promoter Regions, Genetic
Concept Survival Analysis
Concept Genome, Human
Concept Genes, p53
Concept Pathology, Molecular
Concept Genes, Neoplasm
Concept Crosses, Genetic
Concept Enhancer Elements, Genetic
Concept Epistasis, Genetic
Concept Genetic Testing
Concept Translocation, Genetic
Concept Sequence Analysis, RNA
Concept Genetic Predisposition to Disease
Concept Polymorphism, Single Nucleotide
Concept Epigenesis, Genetic
Academic Article 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells.
Academic Article An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
Academic Article Genetic pathways leading to therapy-related myeloid neoplasms.
Academic Article Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells.
Academic Article Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells.
Academic Article CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
Academic Article Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
Academic Article The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
Academic Article Widespread genetic epistasis among cancer genes.
Academic Article Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Academic Article Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Academic Article Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays.
Academic Article Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.
Academic Article The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Academic Article Therapy-related myeloid neoplasms: when genetics and environment collide.
Academic Article System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.
Academic Article A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
Academic Article Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.
Academic Article Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Academic Article Genomic studies controvert the existence of the CUX1 p75 isoform.
Academic Article Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms.
Academic Article Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells.
Concept Clustered Regularly Interspaced Short Palindromic Repeats
Grant Next-Generation Sequencing of Therapy-Related Acute Myeloid Leukemia
Grant Determining the role of CUX1 in myeloid neoplasia
Search Criteria
  • Molecular
  • analysis
  • genetic
  • pathways
  • leading
  • myeloid leukemias