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This page shows the details of why an item matched the keywords from your search.
Search Results
Mcnerney, Megan
One or more keywords matched the following properties of
Mcnerney, Megan
Property
Value
keywords
Myeloid Leukemia
One or more keywords matched the following items that are connected to
Mcnerney, Megan
Item Type
Name
Concept
Base Sequence
Concept
DNA Mutational Analysis
Concept
Genes, MHC Class I
Concept
Nucleic Acid Conformation
Concept
Major Histocompatibility Complex
Concept
Genes, ras
Concept
Transcription, Genetic
Concept
Leukemia, Myeloid
Concept
Genes, Tumor Suppressor
Concept
Leukemia, Myeloid, Acute
Concept
Consensus Sequence
Concept
Evolution, Molecular
Concept
Promoter Regions, Genetic
Concept
Survival Analysis
Concept
Genome, Human
Concept
Genes, p53
Concept
Pathology, Molecular
Concept
Genes, Neoplasm
Concept
Crosses, Genetic
Concept
Enhancer Elements, Genetic
Concept
Epistasis, Genetic
Concept
Genetic Testing
Concept
Translocation, Genetic
Concept
Sequence Analysis, RNA
Concept
Genetic Predisposition to Disease
Concept
Polymorphism, Single Nucleotide
Concept
Epigenesis, Genetic
Academic Article
2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells.
Academic Article
An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
Academic Article
Genetic pathways leading to therapy-related myeloid neoplasms.
Academic Article
Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells.
Academic Article
Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells.
Academic Article
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
Academic Article
Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
Academic Article
The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
Academic Article
Widespread genetic epistasis among cancer genes.
Academic Article
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Academic Article
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Academic Article
Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays.
Academic Article
Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.
Academic Article
The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Academic Article
Therapy-related myeloid neoplasms: when genetics and environment collide.
Academic Article
System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.
Academic Article
A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
Academic Article
Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.
Academic Article
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Academic Article
Genomic studies controvert the existence of the CUX1 p75 isoform.
Academic Article
Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms.
Academic Article
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells.
Concept
Clustered Regularly Interspaced Short Palindromic Repeats
Grant
Next-Generation Sequencing of Therapy-Related Acute Myeloid Leukemia
Grant
Determining the role of CUX1 in myeloid neoplasia
Search Criteria
Molecular
analysis
genetic
pathways
leading
myeloid leukemias